Showing posts with label Proactive. Show all posts
Showing posts with label Proactive. Show all posts

Wednesday, January 26, 2011

ProActive, Hamsters and Science

Photo: courtesy of Maarten Dirkse under the CC license. 


Now, I don't actually care about Chinese hamsters, although I am a very caring person and I love animals.


However, and sadly, Chinese hamsters were used to test the topic effects of benzoyl peroxide, and guess what? They were bad. 


"Benzoyl peroxide, a widely used free radical-generating compound, promoted both papillomas and carcinomas when it was topically applied to mice after 7,12-dimethylbenz[a]anthracene initiation. Benzoyl peroxide was inactive on the skin as a complete carcinogen or as a tumor initiator. A single topical application of benzoyl peroxide produced a marked epidermal hyperplasia and induced a large number of dark basal keratinocytes, effects similar to those produced by the potent tumor promoter 12-O-tetradecanoyl phorbol-13-acetate. Benzoyl peroxide, like other known tumor promoters, also inhibited metabolic cooperation (intercellular communication) in Chinese hamster cells. In view of these results caution should be recommended in the use of this and other free radical-generating compounds."
Source:  ScienceMag.org
Guess in which product you can find benzoyl peroxide.